Reishi Spore Oil Softgel ( Ganoderma Lucidum Spore Oil Softgel) Supplied

Latin Name:Ganoderma lucidum (Leysser.Fr)Karst
Material Original: ZheJiang China
Extracted Part: Spore part
Supported Purity: 100% Organic &  Pure reishi spore oil >30% triterpenoid
Method of Extraction:  CO2 super-critical extraction technology                                                                                                 Capsules Type: 300mg/ capsule, 500mg/capsule
Supplied Quantity: 100,0000 pieces per week for reishi spore oil softgel

reishi spore oil softgel from fungus-extract.com

MIGU’s Reishi Spore Oil Softgel

Ganoderma lucidum is the dry fruiting body of Ganoderma lucidum. Ganoderma lucidum has thousands of years of medicinal history in China. It is a precious traditional Chinese medicine with high medicinal and health value. Ganoderma lucidum spore powder is the germ cell erupted from the cap of Ganoderma lucidum at the mature stage, which has all the genetic active substances of Ganoderma lucidum. Ganoderma lucidum spore powder contains triterpenoids, polysaccharides, fatty acids, amino acids, vitamins and other effective components. Ganoderma lucidum spores are far more effective than their parent Ganoderma lucidum in regulating immunity and anti-tumor effects. Ganoderma lucidum spore oil is a kind of oil mixture obtained by supercritical CO2 fluid extraction of Ganoderma lucidum spore powder.  Ganoderma lucidum spore oil contains triterpenoids, nucleosides and polysaccharides in Ganoderma lucidum spores.

20 Times Concentrated Ganoderma Spore Powder Essence–Reishi Spore Oil

Ganoderma lucidum spore is the seed of Ganoderma lucidum, which concentrates the essence of Ganoderma lucidum. Pharmacological tests show that the efficacy of Ganoderma lucidum spore powder is 75 times that of Ganoderma lucidum. Under the microscope, the spores of Ganoderma lucidum are oval in shape. There is a yellow to bright yellow oil drop in the cytoplasm, which is the reishi spore oil. The spore oil contains 99% of Ganoderma lucidum triterpenoids in Ganoderma lucidum spore powder, which is the core pharmacological component of Ganoderma lucidum spores. Under normal temperature, Ganoderma lucidum spore oil is a light golden yellow translucent liquid with luster and slight sweet and bitter taste. The main components are triterpenoids, Ganoderma acid, unsaturated fatty acid, Ganoderma sterol, etc. scientific identification has proved that the content of Ganoderma triterpenoids in Ganoderma lucidum spore oil is 20 times as much as that of two spore powders. About 1000 g of Ganoderma lucidum spore powder can only extract 10 g of spore oil, so Ganoderma lucidum spore oil also be called ” Golden Oil”

World Advanced Extract Method– CO2 Super-critical Extraction Technology 

Supercritical CO2 extraction technology is the most advanced technology of Ganoderma lucidum spore oil extraction in the world. Taking advantage of the good stability of CO2, the oil  in Ganoderma lucidum spores was extracted in supercritical state, and then the CO2 gas was volatilized by the change of pressure, and the rest will be Ganoderma lucidum spore oil. This process not only does not destroy the active substances of ganoderma spore oil, but also does not need to add chemical solvent such as ethane in the extraction process, so there is no pollution residue in the extraction process, making the extracted reishi spore oil close to the natural state. If the extraction technology is not advanced enough? The nutrition active will be destroy or be affected. Or even can not be extracted the active ingredients enough after extracting which will be difficulty to guarantee the quality and cost.

reishi spore oil softgels extraction -CO2 super-critical

Chemical Composition of Reishi Spore Oil 

The chemical constituents of Ganoderma lucidum spore oil mainly include Ganoderma triterpenoids, Ganoderma acid, organogermanium, Ganoderma lucidum polysaccharide and protein. Chen Tiqiang et al. Identified 18 fatty acids from spore oil extracted by supercritical CO2 by GC-MS, including 6 unsaturated fatty acids, 7 saturated fatty acids, 2 cyclic fatty acids, and short chain fatty acids such as acetic acid, caprylic acid and nonanoic acid. The quantitative analysis results showed that the total amount of unsaturated fatty acids was 73.6%, in which the main components of oleic acid (C18:1), linoleic acid (C18:2) and palmitic acid (c16:0) were 57.5%, 13.4% and 19.6%, respectively; the contents of hexadecanoic acid (c16:1) and linolenic acid (C18:3) were 2.2% and 0.5%, respectively

Pharmacological Action of Reishi Spore Oil Softgel

Antitumor

The effect of Ganoderma lucidum spore oil on tumor growth was dose-dependent. Bian Hao et al. Found that Ganoderma lucidum spore oil could inhibit the growth of H22 transplanted cancer cells. The inhibition rates of three dose groups (3.7, 7.4 and 14.8 g / kg) were 16.2%, 25.8% and 38.8%, respectively. The antitumor effect showed a dose-response relationship. At the same time, Ganoderma lucidum spore oil can reduce the expression of VEGF (vascular endothelial growth factor) in cancer cells. The reason may be that Ganoderma lucidum spore oil can inhibit the growth and migration of vascular endothelial cells by inhibiting the production of VEGF in tumor tissues, thus affecting tumor angiogenesis to achieve the effect of tumor treatment. 8 g / kg * D dose of broken Ganoderma lucidum spores can significantly inhibit the telomerase activity of mouse liver cancer and liver cancer tissue, and effectively destroy the telomerase activity of tumor cancer cells.

Immunomodulation

Liu Juyan and others have found that Ganoderma lucidum spore oil can improve the phagocytosis of mouse peritoneal macrophages, the killing effect of NK cells, and the T cell proliferation reaction induced by concanavalin A (ConA). Bian Hao et al. Determined the content of T lymphocyte subsets, the activity of IL-2 and the proliferative reaction of spleen lymphocytes induced by ConA. The results showed that Ganoderma lucidum spore oil can significantly increase the proportion of peripheral blood CD4 + T cells, reduce the proportion of CD8 + T cells and the height of CD4 + / Chr + value; promote the normal mice to induce IL-2, play the role of endogenous cytokine IL-2; promote ConA induced splenic T lymphocyte proliferation response, so as to improve the specific immune function of the body. Ganoderma lucidum spore oil can enhance the physiological activity of immune cells and restore the function of immune system, which may be one of the mechanisms of its clinical anti-tumor effect.

reishi spore oil softgel planted base from fungus-extract.com

Effects on the Nervous System

Zhu Weiwen has found that in the rat model of 6-hydroxydopamine (6-OHDA) Pakinson disease (PD), the expression of Bax in the ventral part of the brain is increased. Ganoderma lucidum spore oil can effectively reduce the expression of Bax and increase the expression of Bcl-2, and regulate the apoptosis of neurons in substantia nigra caused by 6-OHDA. Ganoderma lucidum spore oil could significantly inhibit MPTP (1 mthyl 4 phenyl 1,2,3, The production of inflammatory cytokine TNF – α and IL-1 β in the midbrain of mice with 6-tetrahydropyridine-induced Parkinson’s disease can reduce the neuroinflammatory reaction of substantia nigra caused by neurotoxin and make dopaminergic neurons continue to survive. This may be one of the main mechanisms of Ganoderma lucidum spore oil in the treatment of MPTP model. Shen Zhiyong et al. Used Ganoderma lucidum spore oil to mice with aluminum poisoning, and found that the learning and memory levels of mice in the prevention and treatment groups were significantly improved, and the pathological damage of ultrastructures such as nerve fibers, mitochondria and synapses in the hippocampus was significantly alleviated. Ganoderma lucidum spore oil has certain preventive and therapeutic effects on central nerve injury caused by aluminum poisoning. The results showed that Ganoderma lucidum could significantly improve the activity of SOD in the anti-aging effect, and had the effect of antioxidant and scavenging free radicals. The reason may be that Ganoderma lucidum spore oil can protect hippocampal nerve tissue of Alzheimer’s disease mice by antioxidation and scavenging free radicals, thus improving the ability of learning and memory.

Lowering blood fat

The concentration of TC (total cholesterin) and HDL-C (high-density lipid cholesterol terol) in serum of male New Zealand rabbits were significantly reduced by supercritical CO2 extraction of ganoderma spore oil

Prevention and treatment of leukemia

Leukemia is a common clinical malignant tumor. At present, the conventional treatment methods are still radiotherapy, chemotherapy and surgery, but these methods have serious side effects and damage the immune function of patients. It was found that the effect of Ganoderma lucidum spore oil on Jurkat cells in vitro for 24 hours showed a significant trend of cell viability and promoting apoptosis, and the effect of spore oil on Jurkat cells was dose-dependent, but the mechanism of its action was still unclear.

Protecting liver

Ganoderma lucidum spore oil can significantly promote the cellular immune function and NK cell activity in mice, and has auxiliary protective effect on CCl4 induced chemical liver injury. The lipid in spores of Ganoderma lucidum could antagonize the liver damage induced by D-galactosamine.

Clinical Application for reishi spore oil softgel 

In 2005, Qian Xiaoqi et al. Used interferon – α 2B combined with Ganoderma lucidum spore oil soft capsule to treat 39 cases of chronic hepatitis B as the experimental group, and 42 cases treated with interferon – α 2B alone as the control group. The results showed that the negative conversion rate of hepatitis B virus DHL (HBV-DNA) in the treatment group was higher than that in the control group after 6 and 12 months. Therefore, interferon – α 2B combined with Ganoderma lucidum spore oil capsule can increase the negative conversion rate of HBV-DNA. More Scientific research and development for reish spore oil softgel , please check here